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Updated: May 20, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
True vignettes: interesting, illustrative examples of behavioral abnormalities in people with Parkinson's disease
Joseph H Friedman1, Umer Akbar2, Blake Beehler3
1Warren Alpert Medical School of Brown University, Butler Hospital, Department of Neurology, Providence RI, USA.
Background:
Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurobehavioral disorders in which behavioral abnormalities are common but often not recognized.
Objective:
To bring to life the actual descriptions rendered by our patients of their unusual experiences.
Methods:
Members of the Parkinson Study Group were asked to provide illustrative examples of particularly memorable abnormal behaviors that their own PD patients or family members reported.
Results:
These recollections were deidentified and sorted into categories. These disorders include the classically described syndromes of Capgras, Cotard, Diogenes, Ekbom, Othello as well as overlap parasomnias, and impulse control disorders.
Conclusion:
Patients with PD often have had unusual experiences that they may not share without inquiries by their healthcare providers, fearful of how they will be perceived. Sensitive inquiries are required to reveal these problems. We believe that reading about real experiences will help sensitize the reader.
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