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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Prepectoral Breast Reconstruction with Polyurethane-Coated Implants: A 117-Patient Single-Center Study with Objective
Sevgi Kurt1, Isil Akgun Demir1, Naci Celik2,3
1Department of Plastic, Reconstructive and Aesthetic Surgery, Istanbul Atlas University, Istanbul, Turkey.
Aesthetic Plastic Surgery
|May 18, 2026
Summary
Polyurethane (PU)-coated implants offer stable prepectoral breast reconstruction with low complication rates. Most patients achieve good cosmetic results, though factors like BMI and implant size influence outcomes.
Area of Science:
- Plastic Surgery
- Breast Reconstruction
- Implant-based Reconstruction
Background:
- Polyurethane (PU)-coated implants are proposed for prepectoral breast reconstruction to improve stability and reduce complications.
- Limited clinical and aesthetic performance data exists for PU-coated implants in this setting.
Purpose of the Study:
- To evaluate the clinical and aesthetic outcomes of prepectoral breast reconstruction using PU-coated implants.
- To identify factors associated with complications and aesthetic satisfaction.
Main Methods:
- Retrospective review of 117 patients (186 breasts) undergoing immediate prepectoral reconstruction with PU-coated implants (2020-2025).
- Complication analysis using univariate and multivariable regression.
- Aesthetic outcome assessment via BCCT.core software.
Main Results:
- At 15-month follow-up, 29.1% experienced complications (e.g., rippling, upper-pole visibility).
- Implant loss (3.4%) and capsular contracture (1.7%) were low.
- 81.2% achieved excellent/good aesthetic results; younger age and absence of complications predicted favorable outcomes.
Conclusions:
- PU-coated implants demonstrate stable outcomes in prepectoral reconstruction with low implant loss and capsular contracture.
- Favorable cosmetic results were achieved in most patients without additional reinforcement.
- Higher BMI, larger implants, smoking, and skin-reducing mastectomy increased complication risk in univariate analysis.
