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Updated: May 20, 2026
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The Intra-Aortic Balloon Pump
Published on: February 5, 2021
Association Between Intra-Aortic Balloon Pump Support and Whole Blood Viscosity Following Cardiopulmonary Bypass
Mehmet Emre Elci1, Gozde Tekin1, Selen Ozturk1
1Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
Artificial Organs
|May 19, 2026
Summary
Intra-aortic balloon pump (IABP) support is linked to lower whole blood viscosity (WBV) after cardiopulmonary bypass (CPB). This suggests IABP may improve hemorheological behavior and microcirculatory flow.
Area of Science:
- Cardiovascular Surgery
- Hemodynamics
- Biomedical Engineering
Background:
- Cardiopulmonary bypass (CPB) can impact blood viscosity.
- Understanding hemorheological changes post-CPB is crucial for patient outcomes.
Purpose of the Study:
- To investigate the association between intra-aortic balloon pump (IABP) support and whole blood viscosity (WBV) in patients undergoing CPB.
- To determine if IABP influences postoperative blood viscosity.
Main Methods:
- Prospective observational study of 80 patients undergoing CPB.
- 40 patients received IABP support; 40 served as controls.
- Whole blood viscosity measured pre- and post-CPB across various shear rates; multivariable regression analysis used.
Main Results:
- Whole blood viscosity decreased post-CPB in both groups.
- IABP group showed significantly lower postoperative WBV at low shear rates (0.6-1 s⁻¹).
- IABP use was independently associated with reduced WBV at 0.6 s⁻¹ and 1 s⁻¹.
Conclusions:
- Intra-aortic balloon pump support is independently associated with reduced whole blood viscosity under low shear conditions post-CPB.
- Findings suggest potential improvements in hemorheological behavior and microcirculatory function with IABP.
- IABP may positively influence tissue perfusion following CPB.
