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Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
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Operationalizing Trauma-Informed Principles to Build Safe, Inclusive, and Equitable Patient Partnerships in Pediatric

Allison M Smith1,2, Sebastian Sachs1,3, Hannah Rogan1

  • 1Department of Anesthesiology, Critical Care, & Pain Medicine, Division of Pain Medicine, Boston Children's Hospital, Brookline, MA, USA.

Journal of Pain Research
|May 19, 2026
PubMed
Summary
This summary is machine-generated.

Trauma-informed principles offer a framework for authentic patient partnerships in pediatric pain research. This approach enhances research rigor, relevance, and ethical integrity by empowering youth and families.

Keywords:
equityinclusivitylived experiencepatient partnershipspediatric paintrauma-informed care

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Published on: January 27, 2010

Area of Science:

  • Pediatric Pain Research
  • Patient Engagement
  • Health Equity

Background:

  • Advancing inclusion in pediatric pain research necessitates authentic partnerships beyond mere recruitment diversity.
  • Limited practical guidance exists for safe, equitable, and sustainable patient-researcher partnerships, particularly with marginalized populations.

Purpose of the Study:

  • To propose trauma-informed principles as a framework for meaningful patient partnerships in pediatric pain science.
  • To synthesize evidence on the benefits of patient engagement for research quality and patient partners.
  • To address barriers to equitable participation and offer actionable strategies.

Main Methods:

  • Synthesized evidence on patient engagement benefits and challenges.
  • Utilized a case example to illustrate patient partner contributions to study design and ethical safeguards.
  • Proposed a partnership framework grounded in trauma-informed care (TIC) principles.

Main Results:

  • Patient partners can significantly shape study design, language, recruitment, and ethical safeguards, enhancing methodological and contextual validity.
  • Identified structural, relational, and emotional barriers to equitable participation.
  • Developed a TIC-based partnership framework linking principles to actionable strategies.

Conclusions:

  • Trauma-informed principles provide a robust framework for authentic patient partnerships in pediatric pain research.
  • Inclusive partnership practices strengthen ethical grounding, methodological rigor, and amplify the voices of youth with pain.
  • Collaborations built on these principles can improve research relevance and impact.