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Related Concept Videos

Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...

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Related Experiment Video

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[Imported Infectious Diseases of the Nervous System].

Hiroyuki Murai1

  • 1Department of Neurology, International University of Health and Welfare.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|May 19, 2026
PubMed
Summary

Imported infectious diseases like dengue fever and measles pose risks in Japan. While Japanese encephalitis and rabies are less common due to vaccinations, vigilance against mosquito and human transmission remains crucial.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Japan generally has good sanitary conditions, but imported infectious diseases are a concern.
  • Dengue fever is globally prevalent, with Japan reporting nearly 200 annual cases, primarily acquired in Southeast Asia.
  • Mosquito-borne diseases like dengue fever and Japanese encephalitis require preventive measures.

Purpose of the Study:

  • To review the status of key infectious diseases in Japan.
  • To highlight the importance of preventive measures against vector-borne and human-to-human transmitted diseases.
  • To discuss the impact of vaccination and public health interventions on disease incidence.

Main Methods:

  • Review of existing data on dengue fever, Japanese encephalitis, rabies, and measles in Japan.

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Listeria monocytogenes Infection of the Brain
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Listeria monocytogenes Infection of the Brain

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  • Analysis of disease transmission routes (mosquito-borne, animal-borne, human-to-human).
  • Assessment of the impact of vaccination programs and control measures.
  • Main Results:

    • Dengue fever incidence is around 200 cases annually, mainly acquired overseas.
    • Japanese encephalitis incidence has decreased due to vaccination, but carries a high mortality rate if symptomatic.
    • Rabies incidence is low due to canine vaccination and stray dog control.
    • Measles, a highly contagious disease, saw a decrease during COVID-19 but is now increasing, with recent cases linked to Vietnam.

    Conclusions:

    • Imported infectious diseases, particularly dengue fever and measles, remain a public health concern in Japan.
    • Vaccination and vector control are effective in reducing the incidence of diseases like Japanese encephalitis and rabies.
    • Continued monitoring and preventive strategies are essential to manage the risk of infectious disease introduction and spread.