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Updated: May 21, 2026

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
Published on: December 19, 2014
[Cryptococcosis]
Kyoko Numahata1, Tomoyuki Miyamoto
1Department of Neurology, Dokkyo Medical University Saitama Medical Center.
Abstract:
Cryptococcosis is an infectious disease caused by encapsulated fungi of the genus Cryptococcus. It predominantly occurs in individuals with impaired immune function, such as those with human immunodeficiency virus (HIV) infection, malignancies, or those having undergone organ transplantation or immunosuppressive therapy. However, it can also occur in healthy individuals. Cryptococcus primarily infects the lungs and central nervous system but can also affect the skin, prostate, peritoneum, and eyes. In this review, we provide an overview of cryptococcosis, with a particular focus on cryptococcal meningitis.
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