Congenital Penile Curvature Is Associated With Larger Penile Dimensions: A Matched Case-Control Study

Area of Science:

• Andrology and Urology
• Human Anatomy and Physiology
• Medical Research Methodology

Background:

• Clinical observations suggest a potential link between congenital penile curvature (CPC) and larger penile dimensions.
• This association has not been objectively investigated, necessitating research to refine morphometric characterization and inform clinical practice.

Purpose of the Study:

• To investigate whether men with CPC exhibit greater stretched penile length (SPL) and mid-shaft penile circumference compared to matched controls.
• To establish objective data for preoperative counseling and normative penile measurement references.

Main Methods:

• A retrospective, matched case-control study involving 50 men with CPC and 100 controls, matched for age, height, and BMI.
• SPL measured under manual traction; mid-shaft circumference measured in the flaccid state.
• Statistical comparison using paired t-tests or Wilcoxon signed-rank tests.

Main Results:

• Men with CPC demonstrated significantly greater SPL (mean difference 1.82 cm) and mid-shaft circumference (mean difference 0.72 cm) compared to controls.
• All anthropometric parameters were adequately balanced between cases and controls.
• Exploratory analysis suggested a correlation between curvature severity and length difference.

Conclusions:

• Congenital penile curvature is associated with significantly larger penile dimensions.
• This finding supports a distinct morphometric pattern in men with CPC.
• Results have implications for surgical counseling, measurement standards, and future research in andrology.