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Related Concept Videos

Energy Balance01:19

Energy Balance

The human body gets energy from the three macronutrients: carbohydrates, proteins, and fats. Energy is released when the chemical bonds in the organic compounds present in the food are broken down. The energy content of food is measured in kilocalories (kcal), defined as the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. This value is determined by measuring the temperature change of the water surrounding a calorimeter after the complete...
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
Metabolic States of the Body: Fasting and Starvation01:24

Metabolic States of the Body: Fasting and Starvation

During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
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Related Experiment Video

Updated: May 21, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
06:13

Solid Plate-based Dietary Restriction in Caenorhabditis elegans

Published on: May 28, 2011

Planetary Health Diet Adherence Improves Weight and Body Composition During Energy Restriction.

Paola Mogna-Peláez1, Naixin Zhang2, Marta Guasch-Ferré2,3

  • 1Department of Nutrition, Food Sciences and Physiology; Centre for Nutrition Research, Institute for Nutrition and Health (INS); IdisNA, University of Navarra, Pamplona, Spain.

Obesity (Silver Spring, Md.)
|May 20, 2026
PubMed
Summary

Adhering to the Planetary Health Diet (PHD) during calorie restriction aids weight loss and improves body composition. Higher PHD adherence is linked to better outcomes, with reduced meat intake and increased whole grains playing a key role.

Keywords:
diet qualitydietary patternsobesity treatmentsustainable nutritionweight loss

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Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
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Published on: November 1, 2019

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Last Updated: May 21, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
06:13

Solid Plate-based Dietary Restriction in Caenorhabditis elegans

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Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
09:10

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents

Published on: November 1, 2019

Area of Science:

  • Nutrition Science
  • Dietary Interventions
  • Obesity Research

Background:

  • Obesity management often involves energy restriction, but the impact of dietary quality on weight loss and body composition is not well understood.
  • The Planetary Health Diet (PHD) offers a framework for healthy and sustainable eating patterns.

Purpose of the Study:

  • To investigate the association between adherence to the Planetary Health Diet (PHD) and weight loss and body composition changes during hypocaloric interventions.
  • To identify specific PHD components that contribute to successful weight management.

Main Methods:

  • Analysis of data from 403 adults with overweight or obesity undergoing two controlled dietary interventions with a 30% energy deficit.
  • Quantification of PHD adherence using an energy-adjusted score based on EAT-Lancet targets.
  • Assessment of associations using mixed models, logistic regression, and mediation analyses, defining excellent weight loss as ≥10% body weight reduction.

Main Results:

  • Higher PHD adherence correlated with lower BMI, waist circumference, and body fat percentage.
  • Participants in the highest adherence quartile showed significantly lower BMI compared to the lowest quartile.
  • Each 10-point increase in PHD adherence increased the odds of achieving ≥10% weight loss by 49%.

Conclusions:

  • Increased adherence to the Planetary Health Diet during energy restriction is associated with greater weight loss.
  • Improved body composition, including reduced body fat, is linked to higher PHD adherence.
  • Reduction in red/processed meat intake and increased whole-grain consumption were identified as key mediating factors for these positive outcomes.