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Updated: May 22, 2026

Novel Object Exploration as a Potential Assay for Higher Order Repetitive Behaviors in Mice
Published on: August 20, 2016
Novelty beyond counting
Christoph Miehl1, Julijana Gjorgjieva2
1Department of Neurobiology, University of Chicago, Chicago, IL, USA; Grossman Center for Quantitative Biology and Human Behavior, University of Chicago, Chicago, IL, USA.
None:
Novelty signals guide learning and exploration. Becker et al.1 show that novelty depends not only on repetition but also on similarity: familiarity generalizes across related stimuli and states, explaining both cortical novelty responses in mouse V1 and novelty-driven maze exploration behavior.
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