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Updated: May 22, 2026
Murine Kidney Transplant Technique
Published on: October 20, 2015
Dengue in Kidney Replacement Therapy: Comparison Between Chronic Dialysis and Kidney Transplant Patients
Ana Vitória Rodrigues de Sá1, Marcela Pagianotto Bidoia1, Ana Carolina Nakamura Tome1
1Hospital de Base de São José do Rio Preto, São Paulo, Brazil; Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
Introduction:
Dengue is the most prevalent arboviral disease in Brazil, and patients on kidney replacement therapy (KRT), such as chronic dialysis (CKD-5D) or kidney transplant recipients (KTx), may present more severe clinical manifestations.
Objective:
This study aimed to compare clinical and laboratory aspects, as well as outcomes of dengue infection, between patients on CKD-5D and KTR.
Methods:
A prospective, analytical, single-center study involving patients diagnosed with dengue (positive NS1 and/or IgM) between November 2024 and April 2025.
Results:
Fifty-eight patients were included (33 CKD-5D and 25 KTx). The median age was higher in CKD-5D patients (67 vs 59 years; p = .0066). The incidence of dengue was 2 times higher in CKD-5D patients (6% vs 2,9%). Hospitalization was more frequent in KTR (92% vs 36.3%; p < .0001), and 56% of them developed acute kidney injury. Lower platelet counts (p = .0164) and being a KTx were independent predictors of hospitalization.
Conclusion:
Despite the higher incidence, advanced age, and presence of comorbidities, patients on CKD-5D presented a lower risk of hospitalization than KTx.
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