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Updated: May 22, 2026
06:46
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Diabetes mellitus-definition, classification, diagnosis, screening and prevention (Update 2026)]
Jürgen Harreiter1,2, Michael Roden3,4,5
1Abteilung für Innere Medizin mit Palliative Care, Landesklinikum Scheibbs, Scheibbs, Österreich.
Wiener Klinische Wochenschrift
|May 20, 2026
Summary
This review compares diabetes mellitus types 1, 2, and MODY, summarizing diagnostic criteria and emphasizing early screening. Early detection and intervention are crucial for managing blood glucose and preventing diabetes progression.
Area of Science:
- Endocrinology
- Metabolic Disorders
- Clinical Biochemistry
Background:
- Diabetes mellitus is a group of heterogeneous disorders characterized by hyperglycemia.
- Understanding different diabetes types is essential for effective management.
- The rising prevalence of diabetes necessitates improved diagnostic and screening strategies.
Purpose of the Study:
- To present the current classification of diabetes mellitus.
- To compare key features of type 1, type 2, and monogenic diabetes (MODY).
- To summarize diagnostic criteria and the role of HbA1c in diabetes detection.
Main Methods:
- Review of current diabetes mellitus classification systems.
- Comparative analysis of clinical and biochemical features of different diabetes types.
- Summary of diagnostic criteria for fasting, oral glucose tolerance tests, and HbA1c.
Main Results:
- Detailed comparison of type 1, type 2, and MODY highlighting distinct characteristics.
- Established biochemical criteria for accurate diabetes diagnosis.
- Emphasis on the utility of HbA1c for diagnosis and monitoring.
Conclusions:
- Accurate classification and diagnosis are fundamental for appropriate diabetes management.
- Targeted screening in at-risk populations is vital for early detection of diabetes and prediabetes.
- Early intervention through lifestyle or pharmacologic measures can prevent or delay diabetes onset and progression.
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