Related Experiment Video
Updated: May 22, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Diabetes mellitus in childhood and adolescence (Update 2026)]
Birgit Rami-Merhar1, Elke Fröhlich-Reiterer2, Sabine E Hofer3
1Universitätsklinik für Kinder- und Jugendheilkunde, Abteilung für Pulmonologie, Allergologie und Endokrinologie, Medizinische Universität Wien, Wien, Österreich. birgit.rami@meduniwien.ac.at.
Abstract:
In contrast to adults, type 1 diabetes mellitus (T1D) is the most frequent form of diabetes in childhood and adolescence (94.2%) in Austria. After diagnosis the management of children and adolescents with T1D should take place in highly specialized pediatric units experienced in pediatric diabetology. The lifelong substitution of insulin is the cornerstone of treatment whereby modalities need to be individually adapted for patient age and the family routine. In this age group the use of diabetes technology (glucose sensors, insulin pumps and automated insulin dosage, AID) is recommended. An optimal metabolic control right from the start of treatment is associated with an improved long-term prognosis. Diabetes education is essential for youth with diabetes and their families and needs to be performed by a multidisciplinary team consisting of pediatric diabetologists, diabetes counsellors, dieticians, psychologists and social workers. The Austrian working group for pediatric endocrinology and diabetes (APEDÖ) and the International Society for Pediatric and Adolescent Diabetes (ISPAD) recommend a metabolic goal of glycated hemoglobin (HbA1c) ≤ 7.0% (International Federation of Clinical Chemistry and Laboratory Medicine, IFCC < 53 mmol/mol) or ≤ 6.5 rel % (IFCC 48 mmol/mol) for those who have access to advanced diabetes technologies, such as AID and a time in range (TIR) of > 70% for all pediatric age groups without the occurrence of severe hypoglycemia. Appropriate age-related physical, cognitive and psychosocial development, screening for associated diseases, avoidance of acute diabetes-related complications (severe hypoglycemia, diabetic ketoacidosis) and prevention of diabetes-related late complications to ensure high quality of life are the main goals of diabetes treatment in all pediatric age groups.
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Type II Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
Diabetes Mellitus: Introduction
