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Updated: May 22, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
A Unique Case Report of Rhabdomyosarcoma Arising Within a Sacrococcygeal Teratoma
Jenusha Felix1, Jyotsna Yesodharan1, Naveen Viswanath2
1Pathology, Amrita Institute of Medical Sciences, Kochi, IND.
Abstract:
Teratomas are germ cell tumours (GCTs) composed of derivatives from one or more of the three germ layers. Sacrococcygeal teratomas (SCTs) are common in the early paediatric age group, with surgical excision being the primary mode of treatment. Malignancy in the context of teratomas occurs either as an immature teratoma or, rarely, as somatic malignancies arising from a germline component within the teratoma. Here, we report an extremely rare case, initially diagnosed as presacral rhabdomyosarcoma, which was subsequently found to have arisen within an SCT in a two-year-old child. To the best of our knowledge, we could not identify a similar case in English literature, and this highlights the need for publication to enable standardisation of management protocols for these extremely rare conditions.
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