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Trends in sudden death-attributed mortality across Europe, 2010-2020: a retrospective population-based analysis
Marco Zuin1,2,3,4, Eloi Marijon5,6, Kumar Narayanan6,7
1Department of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, 44100, Ferrara, Italy.
The Lancet Regional Health. Europe
|May 21, 2026
Summary
Sudden death mortality increased across Europe from 2010-2020, with a faster rise in women. Rates declined in Western Europe but rose in Southern and Eastern Europe, highlighting regional disparities.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Sudden death is a significant global health concern.
- European trends in sudden death mortality require detailed characterization.
Purpose of the Study:
- To analyze sudden death mortality trends in Europe between 2010 and 2020.
- To assess variations in these trends by age, sex, and geographic region.
Main Methods:
- Utilized World Health Organization mortality data (2010-2020) for 26 European countries.
- Analyzed age-adjusted mortality rates (AAMRs) using joinpoint regression.
- Calculated average annual percent change (AAPC) and compared trends across demographic and regional groups.
Main Results:
- A total of 2,583,559 sudden deaths were recorded.
- Overall AAMR increased by 2.9% annually, with a significantly higher increase in women (+2.9%) compared to men.
- Mortality rates decreased in Western Europe (-2.0%) but increased in Southern (+3.3%) and Eastern Europe (+3.4%).
Conclusions:
- Rising sudden death rates in Europe are linked to sex- and region-specific factors, including cardiovascular risk in women.
- Disparities in trends across European regions necessitate tailored public health strategies.
- Multidisciplinary approaches are crucial for addressing increasing sudden death mortality.
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