Related Experiment Video
Updated: May 22, 2026

04:41
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
Published on: March 10, 2023
A Stepwise Approach to Laparoscopic Mesohepatectomy: From Complexity to Standardization with Video Demonstration.
Alessandro Ferrero1, Roberto Lo Tesoriere2, Andrea Pierluigi Fontana1
1Department of General and Oncological Surgery, Ospedale Mauriziano Umberto I, Turin, Italy.
Annals of Surgical Oncology
|May 21, 2026
Summary
This study presents a standardized laparoscopic mesohepatectomy technique for centrally located liver tumors. The stepwise approach ensures safety and reproducibility for this complex oncologic liver surgery.
Area of Science:
- Hepatobiliary Surgery
- Minimally Invasive Oncologic Procedures
- Surgical Standardization
Background:
- Mesohepatectomy is indicated for centrally located liver tumors when parenchymal-sparing approaches are not feasible.
- The procedure involves complex anatomical considerations, including managing major hepatic veins and sectorial inflows.
- Minimally invasive techniques like laparoscopic and robotic surgery are increasingly used for mesohepatectomy.
Purpose of the Study:
- To describe a standardized laparoscopic technique for mesohepatectomy.
- To provide a stepwise approach for safely performing this complex liver surgery.
- To highlight the role of indocyanine green (ICG) guidance in anatomical landmark identification.
Main Methods:
- A five-trocar laparoscopic technique without liver mobilization was employed.
- The procedure followed five sequential steps: Glissonean pedicle approach, inflow occlusion, hepatic vein dissection, and ICG-guided parenchymal transection.
- Indocyanine green (ICG) was used to stain the remnant liver and guide parenchymal transection.
Main Results:
- The technique was demonstrated in a 75-year-old patient with hepatocellular carcinoma.
- The patient experienced an uneventful postoperative recovery.
- The patient was discharged on postoperative day 4.
Conclusions:
- Laparoscopic mesohepatectomy can be safely performed in selected patients.
- Standardization of the surgical steps is crucial for enhancing safety and reproducibility.
- This technique offers a reproducible method for complex liver resections.

