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Related Concept Videos

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Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
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Related Experiment Video

Updated: May 23, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

A Comprehensive Analysis of Prevalence, Risk Stratification, and Early Post-Procedure Predictive Scoring for

Elsayed Ghoneem, Naohisa Yoshida, Ryohei Hirose

    Digestion
    |May 21, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Post-endoscopic submucosal dissection (ESD) coagulation syndrome (PECS) can be predicted using a new scoring system. This tool helps differentiate PECS from delayed perforation (DP) after ESD procedures.

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    Related Experiment Videos

    Last Updated: May 23, 2026

    Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
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    Published on: October 16, 2013

    The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
    04:09

    The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

    Published on: February 13, 2026

    Area of Science:

    • Gastroenterology
    • Endoscopic Procedures
    • Surgical Complications

    Background:

    • Post-endoscopic submucosal dissection (ESD) coagulation syndrome (PECS) presents with abdominal pain and inflammation, mimicking delayed perforation (DP).
    • Accurate differentiation between PECS and DP is crucial for appropriate patient management following ESD.

    Purpose of the Study:

    • To evaluate clinical and biochemical characteristics differentiating PECS from DP after colorectal ESD.
    • To develop and validate a predictive scoring system for early identification of PECS.

    Main Methods:

    • Retrospective analysis of 318 patients undergoing colorectal ESD.
    • Classification into PECS (n=32), DP (n=7), and no-PECS/no-DP (NPD) (n=279) groups.
    • Multivariate analysis to identify PECS predictors, leading to the development of a five-variable PECS-predictive scoring system (FPSS).

    Main Results:

    • The incidence of PECS and DP was 10.1% and 2.2%, respectively.
    • DP showed greater CRP elevation and leukocytosis than PECS.
    • Key predictors for PECS included right colon location, female gender, elevated body temperature, higher day 1 WBC count, and larger lesion size.
    • The FPSS demonstrated an AUC of 0.881 with a high negative predictive value (97.4%).

    Conclusions:

    • The study clarified the distinct characteristics of PECS compared to NPD and DP.
    • The newly developed FPSS offers excellent diagnostic performance for predicting PECS after colorectal ESD.