Related Experiment Video
Updated: May 23, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
Pre-donation deferral patterns in blood donor recruitment in a tertiary care hospital
Poonam Devi1, Neelum Mansoor2, Saba Jamal3
1Dr. Poonam Devi, MBBS., Clinical Laboratories and Blood Transfusion Services, Indus Hospital and Health Network, Karachi, Pakistan.
Objectives:
This study analyzes pre-donation deferral patterns in blood donor recruitment at a tertiary care hospital in Pakistan to improve blood supply management.
Methodology:
A cross-sectional analysis was conducted on 6,039 potential blood donors aged 18-60 years at the Indus Hospital Blood Center, Karachi, from April-June 2023. Physical examinations and clinical evaluations determined the donor's eligibility. Deferral rates and reasons were analyzed using descriptive statistics.
Results:
The average deferral rate was 27.4%, with 97.7% temporary and 2.3% permanent deferral. Majority donors were first-time (92.3%) and male (93.3%). Common temporary deferral reasons were anemia (29.0%), ill-feeling (21.9%), and antibiotic intake (9.8%), while Hepatitis C (23.7%) and Hepatitis B (21.1%), and chronic respiratory disease (18.4%) were permanent.
Conclusion:
The study reveals challenges in blood donor recruitment, including high first-time donors and gender disparity. Targeted measures may help address risk factors and improve donor retention, strengthening blood transfusion services in resource-poor settings, impacting public health in Pakistan and other low- and middle-income countries (LMICs).
More Related Videos
Related Concept Videos
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Kidney Transplant I: Introduction
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

