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Understanding Aggression in SATB2-Associated Syndrome: A Mixed-Methods Study Exploring Caregiver Perspectives.
Lauren Shelley1, Effie Pearson1, Joanne Tarver1
1School of Psychology, College of Health and Life Sciences, Aston University, Birmingham, UK.
Summary
Aggression is common in SATB2-associated syndrome (SAS), often triggered by frustration and anxiety. Understanding these triggers is key for effective behavioral interventions in SAS.
Area of Science:
- Neurodevelopmental Disorders
- Genetics and Rare Diseases
- Behavioral Science
Background:
- SATB2-associated syndrome (SAS) is a genetic disorder causing developmental delay, speech issues, and facial differences.
- Aggression is frequently observed in SAS, but its characteristics and causes are not well understood.
- Caregiver insights are crucial for understanding the lived experience of aggression in SAS.
Purpose of the Study:
- To explore caregiver perspectives on aggression in individuals with SAS.
- To identify common forms, triggers, and contextual factors associated with aggression in SAS.
- To inform the development of targeted behavioral assessments and interventions for SAS.
Main Methods:
- Survey and semi-structured interviews with caregivers of 37 individuals diagnosed with SAS.
- Questionnaires assessed adaptive ability, aggression, and behavioral function.
- Interviews delved into triggers, emotions, and management strategies for aggressive behaviors.
Main Results:
- Aggression was reported in 87% of individuals with SAS.
- Common aggressive acts included pulling/grabbing, hitting with body parts, or objects.
- Triggers frequently involved frustration, anxiety, demands, routine changes, repetitive behaviors, and tangible items.
Conclusions:
- This study offers the first detailed description of aggression within the SAS population.
- Findings highlight specific vulnerabilities and contextual factors contributing to aggression.
- Results can guide the development of tailored behavioral interventions and assessments for SAS.
Keywords:
SATB2SATB2‐associated syndromeaggressionbehavioural functionbehaviours that challengequalitativetriggerMore Related Videos
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