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Green analytical chemistry: From principles to modern evaluation tools
Qisheng Fang1, Xixian Weng1, Xiaorui Qiao1
1School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, PR China.
Talanta
|May 22, 2026
Summary
Green analytical chemistry (GAC) has evolved significantly, with numerous assessment tools now available to evaluate analytical methods. This review critically examines 28 tools, offering guidance for selecting sustainable practices in various scientific fields.
Area of Science:
- Green Analytical Chemistry (GAC)
- Sustainable Analytical Methodologies
- Environmental Footprint Assessment
Background:
- GAC has transitioned from a concept to a crucial discipline driven by global sustainability goals.
- The field has seen substantial growth since the 1999 establishment of the Twelve Principles of Green Chemistry.
- Numerous metrics have been developed to quantify the environmental impact of analytical techniques.
Purpose of the Study:
- To trace the historical evolution of Green Analytical Chemistry (GAC).
- To critically review and compare 28 established green assessment tools for analytical methodologies.
- To discuss emerging paradigms like White Analytical Chemistry (WAC) and Green Sample Preparation principles.
Main Methods:
- Historical development tracing from waste reduction to advanced techniques (e.g., supercritical fluid extraction, microfluidics).
- Critical examination and comparative analysis of 28 specific green assessment tools (e.g., NEMI, GAPI, AGREE, EPPI).
- Discussion of new concepts like White Analytical Chemistry (WAC).
Main Results:
- Identification and detailed examination of 28 distinct green analytical chemistry assessment tools.
- Comparative analysis highlighting the strengths and weaknesses of various evaluation protocols.
- Exploration of emerging trends and principles in sustainable analytical chemistry.
Conclusions:
- The review provides a comprehensive guide for researchers to select and optimize green evaluation protocols.
- Promotes the adoption of sustainable practices in critical areas like pharmaceutical analysis and environmental monitoring.
- Suggests future refinements for green assessment tools to enhance their utility and impact.
Keywords:
Analytical methodsEnvironmental metricsGreen analytical chemistryGreenness assessingSustainability assessmentMore Related Videos
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