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Toward an Ethical Framework for Patient-Facing Artificial Intelligence in Clinical Settings
Meghan Reading Turchioe1, Pooja Desai1, Zayan Reza1
1Columbia University, New York, NY.
Studies in Health Technology and Informatics
|May 23, 2026
Summary
Patient-facing artificial intelligence (AI) in healthcare presents ethical challenges. A framework emphasizes transparency, core principles, and trust for ethical AI implementation, involving patients in decision-making.
Area of Science:
- Medical Ethics
- Health Informatics
- Artificial Intelligence in Healthcare
Background:
- Patient-facing artificial intelligence (AI) is increasingly integrated into clinical settings, shifting patients from passive recipients to active participants in AI-augmented healthcare.
- This transition necessitates a thorough examination of the ethical considerations surrounding the implementation of AI tools that directly interact with patients.
Purpose of the Study:
- To identify and analyze the ethical considerations associated with implementing patient-facing AI in clinical settings.
- To develop a preliminary ethical framework for guiding the responsible deployment of AI in healthcare, using a postpartum depression prediction tool as a specific use case.
Main Methods:
- Conducted 36 qualitative interviews with diverse stakeholders: patients, healthcare professionals, and AI developers.
- Utilized a postpartum depression prediction tool as a concrete use case to explore ethical challenges in patient-facing AI.
Main Results:
- Identified six interconnected themes that formed a preliminary ethical framework.
- The framework highlights transparency as fundamental, balances core ethical principles (autonomy, beneficence, justice, privacy), and recognizes trust as crucial for engagement.
- Ethical implementation involves acknowledging and navigating trade-offs between principles, rather than a mere compliance approach.
Conclusions:
- Ethical implementation of patient-facing AI requires explicit attention to the interplay between core principles and the inherent trade-offs.
- Engaging patients in deliberating context-specific ethical tensions is vital for successful and responsible AI adoption in healthcare.
- Trust emerges as both a prerequisite for and an outcome of ethical patient-AI engagement.
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