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Impact of Digital Platform Engagement by Healthcare Professionals on Patient Adherence to Recombinant Human Growth
Paula van Dommelen1, Lilian Arnaud2, Antonio de Arriba3
1The Netherlands Organisation for Applied Scientific Research TNO, Leiden, The Netherlands.
Abstract:
The Growzen® Connect digital ecosystem has been developed to support treatment for patients on recombinant human growth hormone (r-hGH) therapy. This ecosystem includes electronic injection devices with adherence data transmitters and a platform for healthcare professionals (HCPs) to monitor real-time patient adherence. This study aimed to investigate whether HCPs' engagement with this platform influences adherence to r-hGH therapy in patients from Spain in Argentina. Adherence data (optimal [≥85%] versus suboptimal [<85%]) in the first four years of treatment at the patient level and three clinic-level metrics were extracted from the platform in the year 2024. Patients from Spain and Argentina were selected. We defined three metrics for digital engagement: frequency of monitoring adherence, height data entry, and reported dose changes. Adherence data were obtained from 4,544 patients in 186 clinics in Spain, and 1,550 patients in 184 clinics in Argentina. The proportion of patients with optimal adherence was higher in clinics where HCPs digitally monitored patient adherence data more often, entered more height data in the platform, and more often reported a change in dose. Our research revealed that HCPs' engagement with a digital adherence monitoring platform positively influenced patient adherence to r-hGH therapy in Spain and Argentina.
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