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Updated: Jul 2, 2026

08:47
Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Twenty years of chalazion, big data analysis
Yogev Giladi1,2,3, Alon Tiosano1,2,3, Elad Ben Artsi1,3
1Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Orbit (Amsterdam, Netherlands)
|May 25, 2026
Summary
Chalazion incidence and treatment success are influenced by age and climate. Warmer temperatures correlate with higher chalazion prevalence, and age impacts the need for invasive procedures.
Area of Science:
- Ophthalmology
- Epidemiology
Background:
- Chalazia are common eyelid conditions with varying treatment outcomes.
- Understanding epidemiological patterns is crucial for effective management.
Purpose of the Study:
- To describe large-scale epidemiological patterns of chalazia.
- To assess the outcomes of different chalazion treatments.
Main Methods:
- Retrospective cohort study utilizing electronic medical records from January 2003 to December 2022.
- Analysis of demographic data, medical history, treatments, procedures, and outcomes for over 412,000 patients.
- Statistical analysis to determine treatment efficacy and influencing factors.
Main Results:
- Over 611,000 chalazion diagnoses were recorded.
- Invasive procedures were needed in 9.3% of cases.
- Topical therapies showed varied success rates, with lubricants being most conservative. Incidence strongly correlated with temperature (r=0.71, p<0.001), with higher prevalence above 21°C.
- Invasive intervention rates increased with age (1.8% <18 years, 13.7% >45 years).
Conclusions:
- Most chalazia resolve with conservative management.
- Age and climate are significant factors influencing chalazion incidence and treatment outcomes.
- Findings suggest tailored management strategies based on environmental and demographic factors.

