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The "Cairo Accord"- towards the eradication of RHD: revisited (2026)
Susy Kotit1, Magdi Yacoub1,2
1Aswan Heart Centre, Magdi Yacoub Heart Foundation, Aswan, Egypt.
Frontiers in Cardiovascular Medicine
|May 25, 2026
Summary
Rheumatic heart disease (RHD) is a major global health issue, especially in poorer areas. This article revisits the Cairo Accord to update strategies for RHD eradication, focusing on progress and new recommendations.
Area of Science:
- Cardiology
- Global Health
- Preventive Medicine
Background:
- Rheumatic heart disease (RHD) poses a significant global health burden, disproportionately affecting children and young adults in resource-limited settings.
- RHD is a preventable yet often neglected condition, causing substantial morbidity and mortality worldwide.
Purpose of the Study:
- To revisit the Cairo Accord and outline policy priorities for the eradication of Rheumatic Heart Disease (RHD).
- To present updated recommendations based on progress made since the 2021 update in RHD management and research.
Main Methods:
- Review of recent advancements in RHD research and control strategies.
- Analysis of progress in disease registries, screening, and therapeutic interventions.
Main Results:
- Highlighting significant progress in RHD management and research since the last update.
- Formulating updated recommendations for RHD eradication efforts.
Conclusions:
- Continued focus on disease registries, echocardiographic screening, and genetic research is crucial.
- Accelerating the development of Centers of Excellence and innovative treatments like MV repair and tissue-engineered valves is recommended for RHD eradication.
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