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Sex and age differences in alcohol-attributable mortality in Chile between 2008 and 2022
José Ruiz-Tagle Maturana1,2,3, Francisca Román Mella2,4, Álvaro Castillo-Carniglia2,3
1Fundación Instituto Profesional DUOC UC, Santiago, Chile.
Public Health in Practice (Oxford, England)
|May 25, 2026
Summary
Alcohol-attributable deaths in Chile decreased from 2008 to 2022, but remain a concern. High-risk drinking patterns contribute significantly to alcohol-related harm, especially in younger populations.
Area of Science:
- Public Health
- Epidemiology
- Alcohol Research
Background:
- Alcohol consumption is a leading risk factor for global mortality.
- Understanding trends in alcohol-attributable mortality is crucial for public health interventions.
Purpose of the Study:
- To analyze trends in alcohol-attributable mortality in Chile from 2008 to 2022.
- To examine these trends by sex, age, and cause of death.
Main Methods:
- Secondary analysis of national mortality statistics and drug surveys.
- Estimation of alcohol-attributable fractions (AAFs) using relative risk functions and Monte Carlo simulations.
Main Results:
- Alcohol-attributable mortality decreased from 14.6% in 2008 to 9.6% in 2022.
- Leading causes include liver cirrhosis, injuries, and cardiovascular diseases.
- Males consistently showed higher mortality rates than females, with significant age-related differences in causes.
Conclusions:
- Alcohol-attributable mortality in Chile declined and then stabilized, with persistent sex and age disparities.
- High-risk drinking patterns remain a significant factor in alcohol-related harm.
- Injuries are a major cause of death among younger individuals due to alcohol consumption.
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