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Related Experiment Video

Updated: May 26, 2026

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
07:18

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers

Published on: January 9, 2026

Feeding Practices in Simple Gastroschisis: Insights into Practice Variation from a Multidisciplinary Survey.

Elizabeth Reynolds1, Anjali Cera2, Nicole Cacho2

  • 1Department of Surgery, University of California, Davis Children's Hospital, Sacramento, CA.

Journal of Pediatrics. Clinical Practice
|May 25, 2026
PubMed
Summary

Feeding practices for neonates with simple gastroschisis vary widely. This study highlights the need for standardized, evidence-based guidelines to improve outcomes for these infants receiving enteral nutrition.

Keywords:
congenital anomalyneonatalnutrition

Related Experiment Videos

Last Updated: May 26, 2026

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
07:18

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers

Published on: January 9, 2026

Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery
  • Clinical Nutrition

Background:

  • Limited evidence exists to guide feeding practices for neonates with simple gastroschisis.
  • Current management relies on clinician judgment and historical patterns, leading to variability.
  • Standardization of feeding protocols may improve patient outcomes.

Purpose of the Study:

  • To characterize practice variability in feeding neonates with simple gastroschisis.
  • To identify opportunities for standardizing feeding protocols.
  • To improve clinical outcomes for this patient population.

Main Methods:

  • Cross-sectional survey of neonatal providers regarding feeding practices for simple gastroschisis.
  • Survey focused on initiation and advancement of enteral nutrition post-abdominal closure.
  • Data collected from members of the American Pediatric Surgical Association and AAP Section of Neonatal-Perinatal Medicine.

Main Results:

  • 467 responses analyzed, primarily from neonatologists and pediatric surgeons in academic centers.
  • Near-universal use of enteric drainage tubes (99%) post-abdominal closure.
  • Half of institutions lack gastroschisis feeding protocols; reliance on return of bowel function (84%) for initiating feeds, typically with human milk (86%) at 10-20 mL/kg/day.

Conclusions:

  • Significant variability exists in feeding hospitalized neonates with simple gastroschisis.
  • Development of evidence-based, standardized guidelines is needed.
  • Tailored guidelines can support timely and effective feeding, potentially improving clinical outcomes.