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Updated: May 26, 2026
In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
Published on: July 19, 2024
Improving Care Quality for Metabolic Dysfunction-associated Steatotic Liver Disease Through a Structured Yogic
Gautam Panwar1, Garima Singh2, Kanchan Joshi1
1School of Yogic Science and Naturopathy, Shri Guru Ram Rai University, Dehradun, Uttarakhand, India.
Background:
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease in the world. It is strongly linked to obesity, high blood pressure, type 2 diabetes and dyslipidaemia. Yoga, which includes asanas, pranayama, shat-karmas and meditation, may offer a holistic approach to improve the liver, metabolism and mental health.
Purpose:
To evaluate the effectiveness of a 60-min yoga module in improving liver health and metabolic parameters in MASLD patients.
Methods:
This open-label, two-arm, randomised controlled trial enrolled 72 adults aged 18-60 years diagnosed with MASLD, who received standard care at a hospital in Dehradun. Participants were randomised equally into a yoga group, which received a 60-min online yoga module 5 days per week for 3 months, or a control group receiving standard treatment alone. Key assessments include ultrasound measurement of liver fat, liver enzymes (serum glutamate pyruvate transaminase [SGPT], serum glutamic-oxaloacetic transaminase [SGOT]), HbA1c, lipid profile, body mass index, blood pressure, mental health and quality of life. Data collection occurred at baseline and 3 months post-intervention.
Results:
The study is designed to assess improvements in hepatic steatosis and metabolic and psychosocial parameters following intervention.
Conclusion:
This trial will provide evidence on the role of yoga as an adjunct therapy in MASLD management.
