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Wearable Cardioverter-Defibrillator in Adult Congenital Heart Disease: A Bridge to Decision, Recovery, and Advanced
Berardo Sarubbi1,2, Anna Murredda3, Giovanni Domenico Ciriello3
1Adult Congenital Heart Disease and Congenital and Familial Arrhythmias Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples, 80131, Italy. berardo.sarubbi@collaboratore.uniparthenope.it.
Insights
Sudden cardiac death (SCD) is a risk for adults with congenital heart disease (ACHD). The wearable cardioverter-defibrillator (WCD) offers temporary protection, aiding assessment before permanent device decisions.
Area of Science:
- Cardiology
- Electrophysiology
- Adult Congenital Heart Disease (ACHD)
Background:
- Sudden cardiac death (SCD) is a significant cause of mortality in adults with congenital heart disease (ACHD).
- Risk stratification for ventricular arrhythmias in ACHD is complex due to anatomical and hemodynamic heterogeneity.
- Implantable cardioverter-defibrillator (ICD) implantation in ACHD patients faces challenges like anatomical constraints and device complications.
Purpose of the Study:
- To review the rationale, evidence, and clinical applications of wearable cardioverter-defibrillator (WCD) therapy in ACHD.
- To explore WCD as a temporary solution for arrhythmic risk in ACHD patients with transient conditions.
- To guide decision-making regarding permanent ICD implantation in complex ACHD cases.
Main Methods:
- Literature review of pathophysiological mechanisms and clinical evidence for WCD use in ACHD.
- Analysis of WCD's role in managing temporary increases in arrhythmic risk or impaired ventricular function.
- Discussion of WCD's utility in allowing clinical stabilization and reassessment.
Main Results:
- WCD provides non-invasive, temporary protection against life-threatening ventricular arrhythmias.
- It allows time for stabilization and reassessment in ACHD patients with fluctuating risk.
- WCD can mitigate risks associated with premature or uncertain ICD indications.
Conclusions:
- Wearable cardioverter-defibrillator (WCD) therapy presents a viable non-invasive option for temporary arrhythmia protection in ACHD.
- WCD facilitates individualized decision-making for permanent device therapy in this challenging population.
- Further research into WCD efficacy and long-term outcomes in ACHD is warranted.
Abstract:
Sudden cardiac death (SCD) remains a major cause of mortality among adults with congenital heart disease (ACHD). Risk stratification for malignant ventricular arrhythmias in this population is challenging because of the heterogeneity of anatomical substrates, lifelong haemodynamic changes, and the limited predictive accuracy of currently risk models. Furthermore, implantation of an implantable cardioverter-defibrillator (ICD) in ACHD patients is frequently complicated by anatomical constraints, limited venous access, and a significant burden of device-related complications, including infection involving prosthetic material. Several transient cardiac or systemic conditions-including haemodynamic deterioration, acquired myocardial disease, infections, inflammatory states, pregnancy, endocrine disturbances, or peri-procedural phases-may temporarily increase arrhythmic risk or impair ventricular function. In these scenarios, the indication for permanent ICD may be uncertain or premature. The wearable cardioverter-defibrillator (WCD) provides a non-invasive option for temporary protection against life-threatening ventricular arrhythmias while allowing time for clinical stabilization, diagnostic reassessment, and individualized decision-making. This review summarizes the pathophysiological rationale, available evidence, and potential clinical applications of WCD therapy in ACHD.
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