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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
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Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
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Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: May 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

[Allergic rhinoconjunctivitis].

Howraman Meteran1,2, Simon Høj3, Charlotte Duch Lynggaard3,4

  • 1Lungesygdomme, Københavns Universitetshospital - Hvidovre Hospital.

Ugeskrift for Laeger
|May 26, 2026
PubMed
Summary
This summary is machine-generated.

Allergic rhinoconjunctivitis (AR) diagnosis relies on history and IgE testing. Treatment for moderate-to-severe AR includes intranasal corticosteroids and allergen immunotherapy for long-term benefits.

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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
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Last Updated: May 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
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Published on: September 22, 2023

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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Area of Science:

  • Allergy and Immunology
  • Ophthalmology
  • Otorhinolaryngology

Background:

  • Allergic rhinoconjunctivitis (AR) is a growing health concern impacting daily life and atopic conditions.
  • Accurate diagnosis and severity assessment are crucial for effective management.

Purpose of the Study:

  • To review diagnostic criteria for allergic rhinoconjunctivitis.
  • To outline treatment strategies based on disease severity.
  • To highlight the role of allergen immunotherapy.

Main Methods:

  • Review of current literature on allergic rhinoconjunctivitis diagnosis and treatment.
  • Emphasis on clinical history and IgE sensitization evidence.
  • Utilizing a visual analogue scale (VAS) for severity grading.

Main Results:

  • Diagnosis should integrate patient history with confirmed IgE sensitization.
  • A VAS score < 5 suggests mild AR, while ≥ 5 indicates moderate-to-severe AR.
  • Intranasal corticosteroids are primary for moderate-to-severe AR.

Conclusions:

  • Tailored treatment based on AR severity is recommended.
  • Allergen immunotherapy offers disease-modifying, long-term effects.
  • Evidence-based diagnosis and management are key for AR patients.