A Dual-Branch Deep Learning Framework with Explainability for Dental Caries Classification Using Intra-Oral...

The accurate detection of dental caries is often hindered by modality-specific imaging challenges, such as illumination artifacts in intra-oral photographs and low lesion contrast in radiographs. This study proposes a comprehensive framework comprising three key components: (1) HybridAugment+, an entropy-guided adaptive augmentation strategy that applies stronger transformations to low-information images; (2) DBAttNet, a dual-branch attention network featuring illumination-reflection aware attention (IRAA) for photographs and contrast-frequency-aware attention (CFA) for radiographs; and (3) a CAM-based explainability method, selected through a systematic evaluation of five advanced techniques. This study utilized two datasets derived from public sources, comprising 639 intra-oral photographs (481 caries, 158 healthy) and 456 radiographs (268 caries, 188 healthy). These were annotated by two dentists, with established inter-rater reliability (κ = 0.82 for photographs, κ = 0.79 for radiographs). The experimental results demonstrate that HybridAugment+ improved performance over conventional augmentation by up to 8.72% on photographs and 7.67% on radiographs. Furthermore, DBAttNet achieved F1-scores of 97.90% on photographs and 95.72% on radiographs, outperforming ResNet50, InceptionV3, MSDNet, DCANet, and ARM-Net. A comparative evaluation identified XGrad-CAM as the most suitable explainability method, with optimal visualization thresholds of 30% for photographs and 20% for radiographs. Generalization experiments on ophthalmology (APTOS 2019, Messidor-2) and chest radiography datasets (Kermany CXR, NIH ChestX-ray14) demonstrated consistent performance gains over domain-specific methods (DT-Net, ConvNeXt-Tiny). These results confirm that the core design principles effectively transfer to other modalities facing analogous imaging challenges.