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Improving Vaccine Knowledge Among Adolescents Aged 11-14 Years: A Pre-Post School-Based Educational Intervention
Vincenza Sansone1, Silvia Angelillo2, Concetta Paola Pelullo3
1Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Vaccines
|May 26, 2026
Summary
School-based vaccination education significantly improved vaccine knowledge in Italian adolescents. This intervention shows promise for increasing vaccine literacy and uptake in young people.
Area of Science:
- Public Health
- Pediatric Education
- Vaccinology
Background:
- Schools offer a prime environment for enhancing vaccine literacy and uptake.
- Adolescent vaccination knowledge is crucial for public health initiatives.
- Targeting adolescents can improve long-term vaccine compliance.
Purpose of the Study:
- To assess the feasibility and effectiveness of a school-based educational intervention on vaccination.
- To improve vaccine knowledge among Italian adolescents.
- To identify predictors of successful intervention outcomes.
Main Methods:
- A quasi-experimental study involving 262 adolescents in Southern Italy.
- Utilized the European Commission's e-Bug methodology for education.
- Assessed vaccination knowledge via pre- and post-intervention questionnaires, analyzed with Wilcoxon signed-rank test and regression models.
Main Results:
- Significant increase in vaccination knowledge scores post-intervention (from 5.6 to 6.79).
- Factors associated with improvement included fewer cohabitants, lower pre-test scores, clarity of information, and willingness to participate.
- Regression analysis identified key predictors for enhanced vaccine literacy.
Conclusions:
- School-based educational strategies are effective in boosting vaccine literacy among adolescents.
- Interventions can enhance vaccination compliance in this age group.
- Further randomized controlled trials are recommended to validate these findings.
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