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Updated: May 28, 2026

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Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Muscle Coverage With Fibula Flaps Using Fibrin Glue and a Polyglycolic Acid Sheet: A Six-Patient Case Series
Eiji Hirai1,2, Shunji Sarukawa2, Jinsil Park3
1Department of Oral Oncology, Oita Red Cross Hospital, Oita, Japan.
The Journal of Craniofacial Surgery
|May 26, 2026
Summary
This study evaluated fibular bone grafting with the flexor hallucis longus (FHL) muscle and a novel mucosal coverage technique for mandibular defects. The method showed promise for reconstruction, despite some minor complications.
Area of Science:
- Oral and Maxillofacial Surgery
- Reconstructive Surgery
- Biomaterials Science
Background:
- Segmental mandibular defects often require bone grafting for stabilization.
- Current reconstruction methods aim to restore function and aesthetics.
- Novel techniques are explored to improve outcomes and minimize complications.
Purpose of the Study:
- To assess the efficacy of fibular bone grafting combined with the flexor hallucis longus (FHL) muscle.
- To evaluate a modified mucosal coverage technique using fibrin glue and polyglycolic acid (MCFP) for mandibular reconstruction.
- To analyze postsurgical complications and functional outcomes.
Main Methods:
- Six patients with segmental mandibular defects underwent reconstruction.
- Fibular bone graft with FHL muscle was utilized.
- Oral mucosal defects were covered using fibrin glue and polyglycolic acid (MCFP).
Main Results:
- Complete oral wound epithelialization occurred within 1-2 months.
- Postsurgical complications included skin paddle necrosis (2 patients) and neck wound healing issues (3 patients).
- All patients achieved good masticatory function and stable denture support.
Conclusions:
- The fibular bone graft with FHL muscle and MCFP technique offers a viable option for mandibular reconstruction.
- This method provides durable mucosal coverage, aiding denture stability.
- While complications can occur, they are manageable, and the technique shows potential for small intraoral defects.
