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Published on: November 1, 2018
3D Printing for Mitral Valve Disease: A Systematic Review.
Anastasiia Pavlykova-Chertovska1, Shokoufeh Cheheili Sobbi1, Vasyl Lazoryshynets2
1Department of Cardiothoracic Surgery, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
3D printing offers enhanced mitral valve surgery planning and training. Advances in imaging, software, and materials are improving its clinical impact, despite challenges in standardization and accessibility.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Medical Imaging
Background:
- Mitral valve disease is a prevalent and complex cardiac condition.
- Treatment varies due to anatomical and pathological factors, complicating standardized approaches.
- Procedural planning and surgical training are crucial for effective mitral valve disease management.
Purpose of the Study:
- To systematically review 3D printing techniques, materials, and applications in mitral valve disease.
- To focus on the role of 3D printing in procedural planning and simulation for mitral valve surgery.
Main Methods:
- A comprehensive literature search was conducted across PubMed and MEDLINE (1996-August 2025).
- 63 studies involving 3D printing technologies for mitral valve disease were included.
- Data extracted included imaging modalities, software, printing techniques, materials, creation time, and clinical applications.
Main Results:
- CT, 3D transesophageal echocardiography, and MRI were key imaging modalities; CT was most common.
- Software like Mimics, 3D Slicer, and Philips QLAB were used for data segmentation and model generation.
- Stereolithography, fused deposition modeling, and PolyJet were primary printing techniques, utilizing photopolymer resins and thermoplastics. Model creation time ranged from 45 minutes to 72 hours.
Conclusions:
- 3D printing significantly enhances mitral valve surgery through precise planning and training.
- Challenges include standardization and accessibility, but ongoing advancements are expected to broaden clinical impact.
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