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Updated: May 28, 2026

The Establishment of Calvarial Suture-Bony Composite Defects in Rats: A Standardized Model for Suture-Regenerative Therapy Investigation
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Calcium-Chitosan Scaffolds With Simvastatin Enhance Bone Regeneration in Critical-Sized Calvarial Defects in Rats.

Ruan Henrique Delmonica Barra1,2, Elisa Mara de Abreu Furquim1,2, Edilson Ervolino1,3

  • 1Department of Diagnostic and Surgery, Periodontics Division, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
|May 27, 2026
PubMed
Summary

Simvastatin-functionalized chitosan-calcium scaffolds significantly enhance bone regeneration in critical-sized defects. These biomaterials promote osteogenesis and collagen maturation, offering a promising strategy for bone repair.

Failed At:

2026-07-14T07:36:39.394685+00:00

Keywords:
biomaterial scaffoldsbone regenerationsimvastatin

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