Related Experiment Video

Updated: May 28, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

Life-Threatening Aorto-Atrial Erosion Following Transcatheter Ostium Secundum Atrial Septal Defect Closure: A

Silvia Deaconu1,2, Dan Deleanu1, Mircea Ioan Alexandru Bistriceanu3

  • 1Monza-Ares Hospital, 021967 Bucharest, Romania.

Life (Basel, Switzerland)
|May 27, 2026
PubMed

Insights

Cardiac erosion after atrial septal defect (ASD) closure is rare but serious. This review of 40 cases highlights aortic erosion, often linked to device issues and anatomical factors, requiring surgical repair.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Cardiac erosion is a rare, life-threatening complication following transcatheter closure of secundum atrial septal defects (ASD).
  • Existing evidence is limited to case reports and small series, necessitating further comprehensive review.

Purpose of the Study:

  • To synthesize available evidence on aortic and aorto-atrial erosion after transcatheter secundum ASD closure.
  • To identify clinical, anatomical, procedural, and outcome characteristics of this complication.

Main Methods:

  • A systematic case-based review of literature (PubMed, Scopus, Web of Science, CENTRAL) up to January 2026.
  • Inclusion of adult cases with confirmed aortic or aorto-atrial erosion post-ASD closure.
  • Descriptive synthesis of clinical, anatomical, procedural, imaging, management, and outcome data.

Main Results:

  • Forty cases were identified, with a median age of 39.5 years and 27% female.
  • Chest pain was the most common symptom; median time to erosion was 81 days.
  • Deficient retro-aortic rim (22 cases) and device oversizing (17 cases) were frequent findings. All erosions involved the aorta, predominantly aorta-right atrial (21 cases) or aorta-left atrial (14 cases).

Conclusions:

  • Aortic and aorto-atrial erosion is an uncommon yet severe complication of transcatheter ASD closure.
  • Recurrent factors include female sex, deficient retro-aortic rim, device oversizing, and mild aortic root dilation.
  • Early recognition necessitates careful anatomical assessment, multimodality imaging, and ongoing patient follow-up.

Keywords:
aortic erosionaortic perforationaorto-atrial erosionatrial septal defectoccluder

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