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Updated: May 28, 2026

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Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
Published on: May 5, 2020
Facial Nerve Repair Using a Microsurgical Robot System: A Preclinical Study Using a Rat Model
Yasutaka Umemoto1, Naoyuki Hatayama2, Tomohito Okubo2
1From the Department of Plastic and Reconstructive Surgery, Aichi Medical University, Aichi, Japan.
Plastic and Reconstructive Surgery. Global Open
|May 27, 2026
Summary
Robot-assisted surgery effectively repaired rat facial nerves as small as 0.8mm. This robotic approach achieved outcomes comparable to manual suturing, advancing supermicrosurgery for nerve repair.
Area of Science:
- Microsurgery
- Robotic Surgery
- Neurosurgery
Background:
- Robot-assisted surgery is expanding into supermicrosurgical applications.
- Previous success in vascular anastomoses indicates potential for finer surgical tasks.
Purpose of the Study:
- To evaluate a surgical assistant robot for facial nerve neurorrhaphy in a rat model.
- To compare robotic performance against conventional manual microsuturing.
Main Methods:
- Facial nerve coaptation was performed on rats using manual suturing (hand group) or a microsurgical robotic system (robot group).
- Evaluations included suture time, immediate repair continuity, and histological continuity at 14 weeks.
- Functional recovery was assessed via whisker movement and neural tracing.
Main Results:
- A single surgeon could perform the robotic procedure unassisted.
- Robot-repaired nerves as small as 0.8mm were successfully sutured.
- Comparable suture times were achieved by the robot group after initial learning.
- No significant differences in functional or morphological outcomes were found between groups at 14 weeks.
Conclusions:
- Surgical assistant robots can reliably suture small-diameter rat facial nerves.
- Robotic neurorrhaphy yields outcomes equivalent to manual coaptation.
- Findings support robotic systems for trauma and nerve reconstruction, extending supermicrosurgery to peripheral nerve repair.
