Anterior Lens Subluxation and Pseudohypopyon

Asteroid hyalosis is a benign condition caused by refractile particles in the posterior segment, typically discovered incidentally during eye examination. Rarely, these particles may migrate to the anterior chamber due to lens subluxation, trauma, or pressure changes and mimic a pseudohypopyon or iris metastasis. This case report describes a 67-year-old man with acute, painful vision loss in the left eye and elevated intraocular pressure. Slit lamp examination revealed anterior lens subluxation with a pseudohypopyon. This case highlights the diagnostic challenge of asteroid hyalosis presenting as a pseudohypopyon. Thus, a pseudohypopyon in patients with lens subluxation, traumatic lens changes, or pressure gradients should prompt consideration of asteroid hyalosis migration, as delayed diagnosis could impair vision. Early recognition of the potential for migration of asteroid hyalosis, especially in an acute presentation, is crucial for effective management.