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Published on: July 12, 2024
Targeted screening for heart failure in primary care: evidence, challenges and a pathway-first approach to
Saloni Nakhare1, Mihir A Kelshiker1,2, Holly Young3
1National Heart and Lung Institute, Imperial College London, London, UK.
Early heart failure detection in primary care needs targeted screening. This report reviews evidence and pathways for effective heart failure screening strategies to improve patient outcomes.
Area of Science:
- Cardiology and Primary Care Medicine
- Health Services Research
- Medical Informatics
Background:
- Heart failure (HF) diagnosis is often delayed, leading to significant morbidity and mortality.
- Current screening methods in primary care lack scalability and timeliness.
- Targeted screening strategies are emerging as a solution to early HF detection.
Purpose of the Study:
- To synthesize evidence and operational pathways for heart failure screening in primary care.
- To address the heterogeneity of heart failure and its impact on screening design.
- To explore innovative diagnostic tools, including AI and risk prediction models.
Main Methods:
- Systematic literature search of PubMed MEDLINE, EMBASE, and Cochrane Library.
- Inclusion of publications up to January 2026.
- Review of existing screening pathways and implementation studies, including biomarkers and AI-driven tools.
Main Results:
- Heart failure is a complex diagnosis requiring subtype-specific screening approaches.
- Evidence synthesis covers established biomarkers to novel AI-enabled tools.
- Implementation science is crucial for successful technology integration.
Conclusions:
- Effective pathway redesign is key to implementing innovative healthcare technologies.
- Targeted, risk-based screening pathways are essential for improving HF outcomes.
- Pragmatic trials are needed to validate screening effectiveness across diverse patient groups and conditions.
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