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Histiocytic Sarcoma Presenting as a Submandibular Mass in a 93-Year-Old Patient: A Case Report
Evangelos Kostares1, Athina Chatzigavriil1, Georgia Kostare2
1Department of Oral and Maxillofacial Surgery, Dental School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Reports (MDPI)
|May 27, 2026
Summary
This case report details an extremely rare histiocytic sarcoma in a submandibular gland lymph node. Accurate diagnosis requires extensive immunohistochemistry to differentiate from other malignancies.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Histiocytic sarcoma is a rare, aggressive hematopoietic malignancy.
- It is exceptionally uncommon in the head and neck, particularly in salivary gland lymph nodes.
- This study addresses diagnostic challenges and management of this rare entity.
