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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

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Updated: May 28, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

A One Health Perspective on Cancer: A Narrative Review.

Sílvia A C Duarte1,2, Rosário Pinto-Leite3, Felisbina L Queiroga2

  • 1Department of Medical Oncology, Local Health Unit Trás-os-Montes and Alto Douro, 5000-508 Vila Real, Portugal.

Medical Sciences (Basel, Switzerland)
|May 27, 2026
PubMed
Summary
This summary is machine-generated.

Cancer prevention is most effective through a One Health approach, integrating human, animal, and environmental factors. This strategy addresses diverse risks for better global health outcomes.

Keywords:
cancer preventioncomparative oncologyenvironmental risk factorsmicrobiomeone healthpublic health

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Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
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Area of Science:

  • Public Health
  • Environmental Health
  • One Health Framework

Background:

  • Cancer presents a significant global health and economic challenge.
  • Prevention is the most effective cancer control strategy.
  • The One Health approach offers an integrated framework for addressing cancer risk.

Purpose of the Study:

  • To review cancer through a One Health lens.
  • To explore human, environmental, and animal health contributions to cancer prevention.
  • To emphasize the integration of cancer prevention within the One Health framework.

Main Methods:

  • Narrative review of human health aspects, including burden, risk factors, and prevention.
  • Summary of environmental determinants: climate change, pollution, radiation, and food safety.
  • Inclusion of animal health insights from comparative oncology and microbiome research.

Main Results:

  • Human cancer burden is substantial, with lifestyle and infectious factors playing key roles.
  • Environmental factors like pollution and climate change significantly influence cancer risk.
  • Comparative oncology and microbiome research offer translational opportunities for cancer management.

Conclusions:

  • Integrating cancer prevention into the One Health framework is crucial for managing complex health interplays.
  • A multidisciplinary approach can improve public health policies and sustainable prevention.
  • Enhanced early detection and treatment strategies can reduce healthcare costs and improve global health.