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Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
Technical Aspects of Living Donor Intestinal Transplantation
Maria Jimena Alaniz1, Elif Kortan1, Ivo G Tzvetanov1
1Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Abstract:
Irreversible intestinal failure is associated with significant morbidity secondary to parenteral nutrition, including liver dysfunction, infections, and loss of vascular access. Living donor intestinal transplantation (LDITx) offers a potentially curative option, particularly in regions with limited deceased donors. The procedure is technically demanding, requiring meticulous management of small-caliber vascular pedicles and careful perioperative monitoring to minimize vascular complications. Ensuring donor safety through structured multidisciplinary evaluation is paramount. This article provides a detailed overview of LDITx, emphasizing operative techniques, graft procurement, and recipient procedure, highlighting strategies that optimize both donor and recipient outcomes while restoring intestinal function and quality of life.
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