Related Experiment Video
Updated: May 29, 2026
05:39
Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery
Published on: June 23, 2023
Research Advances in Acupuncture Treatment for Chronic Pain
Zhaoyue Chen1, Chuchu Lu1, Linqi Yang2
1Department of Acupuncture and Massage College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Summary
Bibliometric analysis reveals acupuncture research for chronic pain is advancing, focusing on neuroendocrine-immune regulation and molecular mechanisms like epigenetics. Further research is needed to clarify dose-response relationships and molecular interactions for improved pain management.
Area of Science:
- Integrative Medicine
- Pain Management
- Bibliometrics
Background:
- Acupuncture is increasingly explored for chronic pain management.
- Understanding the research landscape is crucial for advancing therapeutic strategies.
Purpose of the Study:
- To systematically analyze the bibliometric data of acupuncture research in chronic pain over the last decade.
- To identify key research areas, developmental trends, and emerging frontiers in this field.
Main Methods:
- Bibliometric analysis of animal experiment publications on acupuncture for chronic pain.
- Data sourced from the Web of Science Core Collection.
- Visual analysis using CiteSpace 6.3.R1 to construct knowledge maps.
Main Results:
- China leads in publication volume; the USA excels in international collaboration.
- Zhejiang Chinese Medicine University and Fang Jianqiao are leading institution and author.
- Research hotspots include neuropathic pain, inflammatory pain, and hyperalgesia, with a focus on inflammatory mechanisms.
Conclusions:
- Acupuncture's mechanism involves neuroendocrine-immune network regulation, targeting peripheral and central sensitization.
- Emerging research explores molecular mechanisms (phosphorylation, signaling pathways, epigenetics), but remains nascent.
- Future research should address molecular-level interactions and dose-response relationships for enhanced clinical application in pain management.
