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Published on: January 29, 2016
Psychological resilience predicts medication adherence in multiple sclerosis.
Elif Yıldıran Teken1,2, Tahir Teken3, Betül Bakay4
1Faculty of Medicine, Department of Psychiatry, Necmettin Erbakan University, Yunus Emre Mah. Beyşehir Cad, Meram No: 281 PK, 42090, Konya, Türkiye.
Psychological resilience is key for medication adherence in people with relapsing-remitting multiple sclerosis (RRMS). Higher resilience independently predicts better adherence, regardless of distress or disability.
Area of Science:
- Neuroscience
- Psychology
- Medical Adherence Research
Background:
- Sustained adherence to disease-modifying therapies is crucial for managing relapsing-remitting multiple sclerosis (RRMS).
- Psychological distress is linked to poor adherence, but the role of psychological resilience is not well understood.
Purpose of the Study:
- To investigate if psychological resilience independently predicts medication adherence (MA) in people with RRMS.
- To assess resilience's association with MA after controlling for distress, quality of life (QoL), and disability.
Main Methods:
- 165 people with RRMS in remission were studied.
- Medication adherence was measured using the Medication Adherence Report Scale.
- Resilience, distress, coping, QoL, and disability (EDSS) were assessed using validated scales. Multivariate logistic regression was employed.
Main Results:
- Participants with good adherence reported significantly higher resilience and better QoL.
- Adherence positively correlated with resilience and negatively with psychological distress.
- Psychological resilience emerged as the sole independent predictor of good adherence (p=.016).
Conclusions:
- Psychological resilience is a vital resource for sustained treatment adherence in RRMS.
- Resilience supports adherence independently of distress, disability, or QoL.
- Clinical practices could benefit from resilience screening and enhancement strategies to improve patient outcomes.
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