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Related Concept Videos

Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...

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Related Experiment Videos

Rethinking mpox: epidemiology, clinical variants, diagnosis, and response.

Renu Thakur1, Devendra Pratap Singh Rajput2, Nikunj Rajkumar Agrawal1

  • 1Department of Pharmacology, All India Institute of Medical Sciences, Raipur, India.

Osong Public Health and Research Perspectives
|May 28, 2026
PubMed
Summary
This summary is machine-generated.

Mpox, or monkeypox, is a global health concern with evolving transmission and clinical features. Understanding these changes is crucial for diagnosis, containment, and future outbreak preparedness.

Keywords:
AtypicalEpidemiologyMpox, monkeypoxOutbreak

Related Experiment Videos

Area of Science:

  • * Public Health and Epidemiology
  • * Infectious Diseases
  • * Viral Zoonoses

Background:

  • * Mpox (monkeypox) has transitioned from a geographically restricted zoonotic disease to a global public health concern.
  • * The 2022 multinational outbreak highlighted significant shifts in mpox transmission dynamics, affected populations, and clinical presentations.
  • * Classical mpox symptoms include fever, lymphadenopathy, and a centrifugal rash, but atypical presentations are increasingly recognized.

Purpose of the Study:

  • * To review the evolving epidemiology of mpox, differentiating between endemic and non-endemic outbreaks.
  • * To describe the spectrum of typical and atypical clinical features of mpox.
  • * To assess diagnostic strategies and evaluate current and emerging vaccine efficacy for mpox.

Main Methods:

  • * Comprehensive literature review synthesizing current evidence on mpox epidemiology and clinical manifestations.
  • * Analysis of diagnostic approaches, including molecular and point-of-care methods.
  • * Evaluation of vaccine efficacy and limitations, referencing JYNNEOS and ACAM2000.

Main Results:

  • * Recent mpox outbreaks exhibit atypical presentations, such as genital lesions and asynchronous rash development, complicating early diagnosis.
  • * Differences in transmission and clinical features exist between endemic and non-endemic mpox outbreaks.
  • * Current diagnostic tools and vaccines (JYNNEOS, ACAM2000) show varying efficacy and limitations.

Conclusions:

  • * Understanding the changing clinical and epidemiological profile of mpox is essential for effective public health response.
  • * Key priorities include enhancing global surveillance, refining case definitions, improving diagnostic access, and ensuring equitable vaccine distribution.
  • * Continued research and preparedness are vital for managing mpox and future viral zoonotic threats.