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Equine Liver Histopathology
1Department of Population Medicine and Diagnostic Sciences, Cornell University College of Veterinary Medicine, 618 Tower Road, VRT T5-010D, Ithaca, NY 14853, USA.
Abstract:
This review summarizes best practices for equine liver biopsy, including when to perform a biopsy, techniques for sample collection and handling, and strategies to optimize diagnostic yield. It discusses the interpretive framework used by pathologists, common diagnostic challenges, and prognostic scoring systems. Limitations such as sampling error and variability among observers are considered alongside ancillary testing, immunohistochemistry, and in situ hybridization. Emphasis is placed on the importance of communication between clinicians and pathologists to maximize diagnostic and prognostic value.
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