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Preoperative Questionnaire Evaluation and Testing for Latex Allergy: A Retrospective Study From 2015 to 2021
Midori Kawasaki-Nagano1, Risa Tamagawa-Mineoka1,2, Koji Masuda1
1Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
The Journal of Dermatology
|May 29, 2026
Summary
Latex allergy screening using questionnaires and diagnostic tests effectively identifies patients at risk. This strategy helps prevent allergic reactions in the perioperative period, improving patient safety.
Area of Science:
- Allergy and Immunology
- Anesthesiology
- Dermatology
Background:
- Latex allergy is a significant concern in the perioperative setting.
- Early identification of latex allergy is crucial for patient safety.
Purpose of the Study:
- To evaluate the effectiveness of a pre-operative latex allergy screening strategy.
- To analyze the diagnostic yield of questionnaires, skin prick tests, and IgE measurements.
Main Methods:
- A standardized questionnaire was used for pre-operative latex allergy screening.
- Patients suspected of allergy underwent skin prick tests (SPTs) and wearing tests.
- Serum-specific IgE antibody titers were measured for diagnosis.
Main Results:
- 467 patients were suspected of latex allergy via questionnaire.
- SPTs were positive in 105 cases, and wearing tests in 10.
- 10 patients were diagnosed with latex allergy; no intraoperative cases occurred.
Conclusions:
- Pre-operative screening combining questionnaires and diagnostic tests is a valuable strategy for identifying latex allergy.
- This approach can help mitigate risks associated with latex allergy in surgical patients.

