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Lateral Orbital Rim Advancement and Balanced Orbital Decompression for Exorbitism Regression in Crouzon Syndrome
1State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhizaoju Road, Huangpu District, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, No. 639, Zhizaoju Road, Huangpu District, Shanghai, China; Center for Basic Medical Research and Innovation in Visual System Diseases, Ministry of Education, China; Chinese Consortium for Thyroid Eye Disease (CCTED), Shanghai, China.
A new minimally invasive technique, LORA-BOD, effectively reduces eye protrusion in Crouzon syndrome patients. This approach offers a less invasive option for adults concerned about exorbitism, improving both appearance and function.
Area of Science:
- Craniofacial Surgery
- Ophthalmology
- Medical Technology
Background:
- Crouzon syndrome causes craniosynostosis with midfacial hypoplasia and exorbitism.
- Current treatments for Crouzon syndrome are invasive and costly.
- Limited options exist for postpubescent patients with mild exorbitism.
Purpose of the Study:
- To introduce and evaluate a minimally invasive technique for Crouzon syndrome.
- To address exorbitism and improve periorbital contour in adult patients.
- To offer a targeted adjunctive option for localized periorbital concerns.
Main Methods:
- A novel technique, lateral orbital rim advancement combined with balanced orbital decompression (LORA-BOD), was developed.
- The technique was applied to three postpubescent patients with Crouzon syndrome.
- Outcomes were assessed using Hertel exophthalmometry and computed tomography measurements.
Main Results:
- Significant reductions in globe protrusion were observed postoperatively.
- Mean reduction in Hertel exophthalmometry was 7.25 mm.
- Computed tomography showed mean reductions of 3.62 mm and 4.29 mm.
- Improvement in exotropia was noted, enhancing function and appearance.
Conclusions:
- LORA-BOD is an effective technique for reducing exorbitism in Crouzon syndrome.
- The procedure offers a less invasive alternative for specific patient groups.
- LORA-BOD demonstrates favorable efficacy and safety for targeted periorbital concerns.
