Unlocking the Bioactive Potential of Capparis multiflora From Northeast India: First-Ever LC-MS Profiling and...

Area of Science:

• Ethnobotany
• Pharmacology
• Phytochemistry

Background:

• Rural communities rely on traditional ethnomedicinal knowledge for healthcare.
• Capparis multiflora stem is traditionally used in Arunachal Pradesh, India, for boils and navel infections.
• Scientific validation of this traditional use is lacking.

Purpose of the Study:

• To scientifically validate the ethnomedicinal use of Capparis multiflora stem and leaves.
• To investigate the antimicrobial, anti-inflammatory, and antioxidant activities of C. multiflora extracts.
• To perform phytochemical profiling of the plant extracts.

Main Methods:

• Extraction of C. multiflora stem and leaves.
• Assessing antimicrobial, anti-inflammatory, and antioxidant activities of extracts.
• Phytochemical profiling using high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).

Main Results:

• C. multiflora extracts exhibited significant antimicrobial, anti-inflammatory, and antioxidant activities.
• HPLC-MS/MS analysis tentatively identified known bioactive compounds.
• The findings support the traditional ethnomedicinal applications of C. multiflora.

Conclusions:

• The study provides scientific evidence for the traditional use of Capparis multiflora stem in managing infections.
• Further research into wound healing and in vivo models is recommended.
• This validates the ethnobotanical importance of C. multiflora in traditional medicine.