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Related Experiment Video

Updated: Jun 2, 2026

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
11:58

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Published on: August 21, 2021

Mesenteric Defects Closure Using N-Hexyl-Cyanoacrylate Surgical Glue During Roux-en-Y Gastric Bypass: A Single-Center

Hashem Moazenzadeh1, Giorgio Badessi1, Yaacov Jaoui1

  • 1Surgery, Cabrol Hospital, CHU de Reims, Université de Reims Champagne Ardenne, Reims, FRA.

Cureus
|June 1, 2026
PubMed
Summary

Surgical glue for mesenteric defect closure after Roux-en-Y gastric bypass shows promising results, with no internal hernias observed in a recent study. Further research is needed to confirm these findings for bariatric surgery patients.

Keywords:
acute intestinal occlusioninternal herniamesenteric defect clotureroux-y-gastric bypasssmall bowel obstructionsurgical glue

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Last Updated: Jun 2, 2026

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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Area of Science:

  • Bariatric Surgery
  • Gastrointestinal Surgery
  • Surgical Innovation

Background:

  • Internal hernia (IH) is a serious complication after minimally invasive Roux-en-Y gastric bypass (mRYGB), occurring in 0.5-9% of patients.
  • Mesenteric defect closure (MDC) is recommended, but suturing carries risks like hemorrhage and hematoma.
  • Surgical glue presents a potential alternative for MDC.

Purpose of the Study:

  • To evaluate the incidence of internal hernias (IH) following the routine use of surgical glue for mesenteric defect closure (MDC) during mRYGB.
  • To assess the feasibility and tolerance of using surgical glue for MDC in bariatric surgery.

Main Methods:

  • An observational study involving 170 consecutive patients undergoing mRYGB with surgical glue for MDC from January 2020 to January 2022.
  • Prospective follow-up data analysis, with a mean follow-up duration of 42 months.

Main Results:

  • No clinically significant internal hernias (IH) were observed in the study cohort.
  • One patient required surgery for acute small bowel obstruction (SBO) but without evidence of IH.
  • The median operative time for glue application was 8 minutes.

Conclusions:

  • Preliminary findings suggest that surgical glue is a feasible and well-tolerated method for mesenteric defect closure (MDC) in mRYGB.
  • The absence of IH in this cohort is encouraging but requires cautious interpretation due to potential biases.
  • Multi-institutional prospective studies are necessary to validate these promising results.