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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

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Updated: Jun 2, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Concurrent Breast and Colon Cancer: Small Cohort Analysis.

Qasif Qavi1, Km Saiful Islam2,3, Zeeshan Hashmi4

  • 1Surgery, Basildon and Thurrock University Hospital, Basildon, GBR.

Cureus
|June 1, 2026
PubMed
Summary
This summary is machine-generated.

Multiple primary malignant neoplasms (MPMNs), including breast and bowel cancers, are increasingly common. These cancers can occur synchronously or metachronously, often requiring a multidisciplinary approach for optimal management.

Keywords:
breast cancercolorectal cancermetachronous cancermultiple primary malignant neoplasmssynchronous cancer

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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

Published on: December 19, 2019

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Last Updated: Jun 2, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Published on: September 27, 2024

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
10:32

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

Published on: December 19, 2019

Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Oncology

Background:

  • Multiple primary malignant neoplasms (MPMNs) are rising due to better diagnostics and survival rates.
  • Genetic mutations, lifestyle, and environmental factors contribute to MPMN development.
  • This study focuses on the clinic-pathological aspects of concurrent breast and bowel cancers in women.

Purpose of the Study:

  • To analyze the characteristics of female patients with synchronous or metachronous bowel and breast cancers.
  • To identify diagnostic challenges associated with these dual malignancies.
  • To outline effective management strategies for patients with both breast and colon cancer.

Main Methods:

  • Retrospective review of 12 female patients diagnosed with both breast and bowel cancer between 2015 and 2025.
  • Analysis included demographics, clinical presentation, imaging, histopathology, genetics, and treatment.
  • Data on synchronous and metachronous diagnoses were specifically examined.

Main Results:

  • The average patient age was 70 years, with 58% of cases being synchronous.
  • Breast cancer was incidentally found during colon cancer staging in 33% of patients.
  • Most breast tumors were invasive carcinoma of no special type, and colonic tumors were predominantly adenocarcinomas.

Conclusions:

  • MPMNs, including breast and colon cancer, are increasingly prevalent across age groups.
  • The co-occurrence of these cancers can happen without clear risk factors.
  • Individualized, multidisciplinary care is essential for timely diagnosis and successful treatment of concurrent breast and colon cancers.