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Anticoagulant Drugs: Low-Molecular-Weight Heparins

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Related Experiment Video

Updated: Jun 2, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
04:23

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

The Use of Hemostatic Agents to Decrease Surgical Drain Time in General Plastic Surgery Procedures.

Austin Olano1, Saman Namazian2, Alexander Martin2

  • 1From the Tufts Medical Center, Department of Surgery, Boston, MA.

Plastic and Reconstructive Surgery. Global Open
|June 1, 2026
PubMed
Summary
This summary is machine-generated.

Hemostatic agents significantly reduce surgical drain time in plastic surgery. Combination powder was more effective than fibrin sealant, decreasing drain duration in abdominoplasty, panniculectomy, and breast reduction procedures.

Related Experiment Videos

Last Updated: Jun 2, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
04:23

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

Area of Science:

  • Plastic Surgery
  • Surgical Innovation
  • Postoperative Care

Background:

  • Surgical drains are common in plastic surgery due to extensive tissue undermining.
  • The study aimed to evaluate the impact of hemostatic agents on drain duration.
  • Secondary goals included assessing the effect on seroma and hematoma rates.

Purpose of the Study:

  • To determine if hemostatic agents reduce surgical drain time in plastic surgery.
  • To investigate the impact of specific hemostatic agents (fibrin sealant, combination powder) on drain duration.
  • To assess the effect of hemostatic agents on postoperative complications like seromas and hematomas.

Main Methods:

  • Retrospective chart review of 351 patients undergoing abdominoplasty, panniculectomy, or bilateral breast reduction.
  • Data collection included hemostatic agent use (fibrin sealant, combination powder), drain removal time, and complications.
  • Statistical analysis employed t tests and Fisher exact test.

Main Results:

  • Combination powder significantly reduced drain duration in abdominoplasty/panniculectomy (13.5 vs. 27.9 days) and BBR (7.1 vs. 8.7 days).
  • No significant differences in hematoma, seroma, or reintervention rates were observed among groups.
  • Hemostatic agents, particularly combination powder, demonstrated efficacy in shortening drain time.

Conclusions:

  • Hemostatic agents, including fibrin sealant and combination powder, are associated with significantly reduced postoperative surgical drain duration.
  • The findings support the use of hemostatic agents to optimize recovery in plastic surgery.
  • Further research may explore optimal agent selection for different procedures.